
In announcing the award, UNESCO recognized Prof. Ip as an internationally renowned neuroscientist whose research has significantly advanced the understanding of brain function and neurodegenerative diseases. It highlighted her team’s discoveries of novel biomarkers and genetic risk factors for Alzheimer’s disease, the development of an innovative blood-based diagnostic technology that enables earlier detection and monitoring of the disease, and her pioneering advances in gene therapy research that have opened new avenues for the prevention and treatment of neurodegenerative disorders.
President Prof. Nancy Ip first received the L’Oréal-UNESCO For Women in Science Award in 2004, becoming the first Chinese scientist in the life sciences and the first scientist from Hong Kong to receive the honor. Her latest recognition, the 2026 UNESCO-Equatorial Guinea International Prize for Research in the Life Sciences, marks a second major accolade from UNESCO and makes her the first Hong Kong scientist to have received both prestigious UNESCO awards.
Receiving the award in Paris, Prof. Ip expressed her heartfelt gratitude to her research team, collaborators and colleagues, and thanked HKUST for its steadfast support throughout her scientific journey.

Prof. Ip said: “I am deeply honored to receive the UNESCO-Equatorial Guinea International Prize for Research in the Life Sciences. This recognition belongs not only to me, but also to the many talented and dedicated team members, collaborators and colleagues who have contributed to these achievements. It reflects our shared commitment to advancing knowledge, deepening our understanding of Alzheimer’s disease, and translating scientific discoveries into meaningful benefits for patients and society.“
She added: “Alzheimer’s disease is not just a scientific and medical challenge. It is also a deeply human one, profoundly affecting the lives of those living with the disease and their families. Their courage reminds us why our work matters and inspires us to reach higher.”
Prof. Ip also emphasized the importance of global scientific collaboration and nurturing future generations of researchers. “Science is a collective endeavor,” she said. “Every breakthrough is built on collaboration across disciplines, institutions and borders. As a scientist and university president, I believe we must also empower young researchers by giving them the freedom to pursue their curiosity, the confidence to take intellectual risks, and the support they need to tackle the grand challenges facing humanity.”

Breakthrough Contributions to Neuroscience and Alzheimer’s Disease Research
Prof. Ip has devoted more than three decades to advancing research on neurodegenerative diseases. To date, she has published over 350 scholarly papers and holds 144 patents. Her pioneering work has significantly deepened scientific understanding of intercellular communication in the nervous system, synaptic signaling, and the molecular mechanisms underlying neurodegenerative diseases. Her research team has also achieved a series of breakthroughs in identifying protein targets associated with these disorders, opening new avenues for their diagnosis and treatment.
Recognizing that Alzheimer’s disease research has historically relied heavily on data from Western populations, with Asian populations being relatively underrepresented, Prof. Ip led her team in establishing a large-scale Chinese Alzheimer’s disease biobank. By integrating clinical data, neuroimaging information, and multi-omics datasets from Chinese populations, the team successfully identified multiple genetic risk factors prevalent among Chinese individuals. These findings have provided important scientific insights into disease mechanisms and laid a foundation for the development of precision diagnostic and therapeutic strategies.
In recent years, Prof. Ip and her team have made significant advances in the early detection of Alzheimer’s disease and the clinical translation of related research. They co-developed a highly accurate, minimally invasive, and efficient blood-based diagnostic test that can aid early detection of Alzheimer’s disease and help identify individuals with mild cognitive impairment, thereby supporting timely clinical assessment and intervention planning, as well as the identification of suitable participants for clinical trials. The technology has been adopted by multiple healthcare institutions in Hong Kong and has since been expanded into community settings, helping to inform more effective disease management and risk-reduction strategies. Meanwhile, the team is actively exploring novel gene therapy approaches for familial Alzheimer’s disease through gene-editing technologies, with the goal of developing an integrated innovation pipeline spanning early diagnosis to next-generation therapeutics.
An Internationally Acclaimed Scientist
Prof. Ip is President of The Hong Kong University of Science and Technology (HKUST) and concurrently serves as Director of the State Key Laboratory of Nervous System Disorders and Director of the Hong Kong Center for Neurodegenerative Diseases. Prior to joining HKUST, she was a Senior Staff Scientist at Regeneron Pharmaceuticals in the United States. Since joining HKUST, she has held a number of key leadership positions, including Head of the Department of Biochemistry, Dean of Science, and Vice-President for Research and Development, before assuming the presidency of the University in 2022.
Renowned internationally for her scientific achievements and academic leadership, Prof. Ip is an elected member of the Chinese Academy of Sciences, the US National Academy of Sciences, the American Academy of Arts and Sciences, The World Academy of Sciences (TWAS), Academia Europaea, and the Hong Kong Academy of Sciences. Her many honors include the L’Oréal-UNESCO For Women in Science Award, the State Natural Science Award of China (twice), and recognition by Nature as one of China’s “Ten Science Stars”. She was also appointed Chevalier de l’Ordre National du Mérite by the French Government and awarded both the Silver Bauhinia Star and Bronze Bauhinia Star by the HKSAR Government.
The UNESCO-Equatorial Guinea International Prize for Research in the Life Sciences was established by UNESCO to recognize outstanding scientific achievements that advance human health and improve quality of life. The Prize promotes scientific excellence, international collaboration, and the development of research networks worldwide. This year’s prize is shared by three laureates, who jointly receive US$300,000 and an Integración Tribal statuette created by Equatorial Guinean artist Leandro Mbomio Nsue.
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